About Prima Mente

Prima Mente is a frontier biology AI lab. We generate our own data, build general purpose biological foundation models, and translate discoveries into research and clinical outcomes. Our first goal is to tackle the brain: to deeply understand it, protect it from neurological disease, and enhance it in health. Our team of AI researchers, experimentalists, clinicians, and operators is based in London, San Francisco and Dubai.

About this role

This role is the operational backbone of our clinical programs.

As a CRA / Clinical Research Operator, you are the person who ensures that nothing falls through the cracks — documentation is correct, audit trails are clean, logistics are tracked, and sites have what they need to operate compliantly.

This is a hands-on, detail-oriented role for someone who takes pride in doing things properly.

Regular UK site visits; occasional international travel.

Role focus

As a CRA / Clinical Research Operator, you will support clinical delivery by owning the administrative and compliance-heavy work that keeps studies running smoothly.

You’ll work closely with Project Managers, sites, labs, and internal teams to ensure documentation, logistics, and systems are always up to date and audit-ready.

What you’ll work on

• Manage site documentation: ICFs, delegation logs, training logs, consent records, and document reconciliation.

• Ensure audit trails are complete, accurate, and inspection-ready.

• Support site initiation and ongoing site operations through documentation and admin.

• Track and manage kit logistics, sample usage, storage, and courier coordination.

• Monitor sample tracking and escalate discrepancies quickly.

• Maintain Trial Master File (TMF) contributions and QC.

• Support monitoring visits through preparation, follow-up, and documentation.

• Act as a reliable operational partner to Project Managers and sites.
  

What we’re looking for

We’re looking for someone who is highly dependable, organised, and eager to grow — someone who takes pride in operational excellence.

You’ll likely recognise yourself in several of these:

• Detail-oriented operator 0–4 years experience as a CRA, CTA, or similar role.

• Strong documentation instincts You care about accuracy, version control, and clean records.

• Operationally minded You enjoy tracking logistics, reconciling information, and keeping systems up to date.

• Reliable and calm under pressure You follow through and communicate clearly when issues arise.

• Mission-aligned You care about patient impact and want to build a career in clinical research and biotech.
  

Growth expectations

In your first month

• You understand our systems, SOPs, and documentation standards.

• You’re supporting multiple sites administratively.

• You’re trusted with core operational tasks.

• You proactively flag risks and discrepancies.
  

By two months

• You independently manage site documentation and logistics.

• You’re a reliable support partner to PMs and sites.

• You are a go-to operator for audit readiness and site admin.
  

By three months

• You’ve helped improve how we manage documentation and logistics at scale.

• You’re contributing to best practice across studies.
  

This role is not for you if

• You dislike detailed administrative work.

• You’re uncomfortable with documentation and compliance.

• You want a purely strategic role early in your career.
  

Why join Prima Mente

If you want to learn fast, build strong fundamentals, and be trusted with real responsibility in cutting-edge clinical research, we’d love to hear from you.

Culture Insight

What we are doing is extremely hard. Prima Mente is for great people. We are team players who appreciate challenges, want to be hands-on, and thrive on curiosity by throwing away assumptions. We are focused on excellence at pace and huge personal growth. We are strong communicators who are highly disciplined and rigorous.

Prima Mente operates with a flat organizational structure. We gain and share knowledge by contributing to multiple opportunities. Leadership is given to those who show initiative and consistently deliver excellence.

We arrange our lives so we can work in person as much as possible.

Our Values

Exceptional performance at exceptional pace

• The solutions we build demand uncompromising quality and rigour.

• The problems we are solving are grave and present.

Inquisitive discovery

• We embrace curiosity and creativity.

• Every question is a path to a transformational breakthrough.

Radical candour

• We practice unwavering honesty and transparency in all our challenges and interactions.

Purposeful individuality

• Every individual in our team is celebrated for their identity, uniqueness, and experiences.

• We are invested in each one’s bespoke personal development.

• Nurturing individuality will supercharge our collective purpose and spirit.

Patient impact at scale

• We have a steadfast commitment to improve the health and well-being of patients globally.

• Every experiment run, every dataset analysed, and every innovation developed, is a step towards achieving a scalable impact.